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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1E
All Species:
9.09
Human Site:
S2
Identified Species:
20
UniProt:
P10412
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10412
NP_005312.1
219
21865
S2
_
_
_
_
_
_
M
S
E
T
A
P
A
A
P
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
E3
_
_
_
_
_
M
S
E
T
A
P
V
A
P
T
Rhesus Macaque
Macaca mulatta
P40286
208
22075
P6
_
_
M
S
E
T
V
P
A
A
S
A
G
A
V
Dog
Lupus familis
XP_853847
290
29282
K57
D
P
K
P
T
V
S
K
T
A
P
A
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
S2
_
_
_
_
_
_
M
S
E
T
A
P
A
A
P
Rat
Rattus norvegicus
P15865
219
21969
S2
_
_
_
_
_
_
M
S
E
T
A
P
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
A2
_
_
_
_
_
_
M
A
E
T
A
P
T
A
P
Chicken
Gallus gallus
P08284
219
22026
E3
_
_
_
_
_
M
S
E
T
A
P
A
A
A
P
Frog
Xenopus laevis
P06893
220
22422
E6
_
_
M
T
A
T
T
E
T
A
P
V
A
P
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
P12
A
V
A
T
S
A
S
P
V
A
A
P
P
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
A2
_
_
_
_
_
_
M
A
E
K
N
S
S
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
55.7
57.2
N.A.
94
95.4
N.A.
79.8
73.9
58.6
N.A.
N.A.
43.3
N.A.
N.A.
41.1
Protein Similarity:
100
87.3
68
62
N.A.
95.4
97.2
N.A.
87
79.4
66.3
N.A.
N.A.
52.3
N.A.
N.A.
50.6
P-Site Identity:
100
10
7.6
13.3
N.A.
100
100
N.A.
77.7
30
15.3
N.A.
N.A.
20
N.A.
N.A.
22.2
P-Site Similarity:
100
10
23
13.3
N.A.
100
100
N.A.
88.8
30
15.3
N.A.
N.A.
20
N.A.
N.A.
44.4
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
10
0
19
10
55
46
28
64
64
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
28
46
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
10
0
0
0
10
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
19
0
0
19
46
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
19
0
0
37
46
10
28
64
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
0
37
28
0
0
10
10
10
0
0
% S
% Thr:
0
0
0
19
10
19
10
0
37
37
0
0
10
0
19
% T
% Val:
0
10
0
0
0
10
10
0
10
0
0
19
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
82
82
64
64
64
46
0
0
0
0
0
0
0
0
0
% _